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产品目录

CD13/ANPEP抗体图片
产品货号:
Z13208
中文名称:
CD13/ANPEP抗体
英文名称:
Anti-CD13/ANPEP Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-CD13/ANPEP Antibody
指标别名Alanyl aminopeptidase;Aminopeptidase M;Aminopeptidase N;ANPEP;AP M;AP N;APN;CD13;gp150;hAPN;LAP1;Microsomal aminopeptidase;p150;PEPN
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,FCM,ELISA
基因名称ANPEP
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human CD13/ANPEP recombinant protein (Position:D148-S966).
实际分子量150KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.It is mapped to 15q26.1.Aminopeptidase N is located in the small-intestinal and renal microvillar membrane,and also in other plasma membranes.In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases.Its function in proximal tubular epithelial cells and other cell types is less clear.The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily.Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical.The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types,including small intestinal and renal tubular epithelial cells,macrophages,granulocytes,and synaptic membranes from the CNS.Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections.Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Uniprot IDP15144
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称alanyl aminopeptidase,membrane
蛋白名全称Aminopeptidase N
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
ELISA: 1:100~1000
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:CD13/ANPEP抗体CD13抗体ANPEP多抗Anti-CD13/ANPEP Antibody
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