产品货号：
Z13208
中文名称：
CD13/ANPEP抗体
英文名称：
Anti-CD13/ANPEP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD13/ANPEP Antibody |
| 指标别名 | Alanyl aminopeptidase;Aminopeptidase M;Aminopeptidase N;ANPEP;AP M;AP N;APN;CD13;gp150;hAPN;LAP1;Microsomal aminopeptidase;p150;PEPN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | ANPEP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CD13/ANPEP recombinant protein (Position:D148-S966). |
| 实际分子量 | 150KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.It is mapped to 15q26.1.Aminopeptidase N is located in the small-intestinal and renal microvillar membrane,and also in other plasma membranes.In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases.Its function in proximal tubular epithelial cells and other cell types is less clear.The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily.Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical.The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types,including small intestinal and renal tubular epithelial cells,macrophages,granulocytes,and synaptic membranes from the CNS.Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections.Defects in this gene appear to be a cause of various types of leukemia or lymphoma. |
| Uniprot ID | P15144 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | alanyl aminopeptidase,membrane |
| 蛋白名全称 | Aminopeptidase N |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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