产品货号：
Z12981
中文名称：
CD25/IL2RA抗体
英文名称：
Anti-CD25/IL2RA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD25/IL2RA Antibody |
| 指标别名 | CD25;IDDM10;IL 2 RA;IL 2 receptor subunit alpha;IL 2R subunit alpha;IL2 RA;IL2R;IL2RA;interleukin 2 receptor;alpha;p55;TAC antigen;TCGFR |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | IL2RA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human CD25/IL-2sR Alpha(39-57aa MAYKEGTMLNCECKRGFRR). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | IL2RA(Interleukin 2 receptor,alpha),also called IL2R,IL2R,Alpha Chain or CD25,is a protein that in humans is encoded by the IL2RA gene.The IL2RA gene is mapped on 10p15.1.IL2RA is composed of strand-swapped "sushi-like" domains,unlike the classical cytokine receptor fold.As a result of this domain swap,IL2RA uses a composite surface to dock into a groove on IL2 that also serves as a binding site for antagonist drugs.Homodimeric alpha chains(IL2RA) result in low-affinity receptor,while homodimeric beta(IL2RB) chains produce a medium-affinity receptor.Normally an integral-membrane protein,soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.Infection by the protozoan Trypanosoma cruzi causes Chagas disease,characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells.This leads to chronic immune suppression,becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated. |
| Uniprot ID | P01589 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | interleukin 2 receptor,alpha |
| 蛋白名全称 | Interleukin-2 receptor subunit alpha(IL-2 receptor subunit alpha/IL-2-RA/IL-2R subunit alpha/IL2-RA) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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