产品货号:
Z12893
中文名称:
BRSK2抗体
英文名称:
Anti-BRSK2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BRSK2 Antibody |
指标别名 | BR serine/threonine kinase 2;BRSK2;C11orf7;PEN11B;SAD1;STK29 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,FCM,ELISA |
基因名称 | BRSK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human BRSK2 recombinant protein (Position:M250-P736). |
实际分子量 | 90KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene.BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C.elegans neuronal cell polarity regulator SAD1.BRSK2 is expressed in the brain and to a lesser extent in the testes.BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1.More recently,it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization.While BRSK1- and BRSK2-null mice were viable,double-mutant mice died within two hours of birth.Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites.These neurites also displayed both axonal and dendritic markers.BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis.At least four isoforms of BRSK2 are known to exist. |
Uniprot ID | Q8IWQ3 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | BR serine/threonine kinase 2 |
蛋白名全称 | Serine/threonine-protein kinase BRSK2 |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 |
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