产品货号：
Z12792
中文名称：
CD16/FCGR3A抗体
英文名称：
Anti-CD16/FCGR3A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD16/FCGR3A Antibody |
| 指标别名 | CD16;CD16A;CD16a antigen;Fc gamma RIII;Fc gamma RIII alpha;Fc gamma RIIIa;FCG3;FCGR3;FCGR3A;FCGRIII;FCR 10;FCRIII;FCRIIIA;IGFR3;IgG Fc receptor III 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,ICC/IF,FCM,ELISA |
| 基因名称 | FCGR3A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CD16 recombinant protein (Position:Q101-D166). |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene.This gene encodes a receptor for the Fc portion of immunoglobulin G,and it is involved in the removal of antigen-antibody complexes from the circulation,as well as other other antibody-dependent responses.This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1.The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide,whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.Mutations in this gene have been linked to susceptibility to recurrent viral infections,susceptibility to systemic lupus erythematosus,and alloimmune neonatal neutropenia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P08637 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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