产品货号：
Z12729
中文名称：
Caspase 9/CASP9抗体
英文名称：
Anti-Caspase 9/CASP9 Antibody
产品规格：
100μg(vial)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caspase 9/CASP9 Antibody |
| 指标别名 | APAF 3;APAF3;Apoptotic protease Mch 6;CASP 9;CASP9;Caspase 9;Caspase 9/p35/p10;CASPASE 9c;Caspase9;Caspase-9;ICE LAP6;ICE like apoptotic protease 6;MCH6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | CASP9 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Recombinant human procaspase-9 (N-terminal fragment). |
| 计算分子量 | 46kDa |
| 成分 | Each vial contains 0.09% sodium azide. |
| 纯化方式 | Protein A affinity purified. |
| 浓度 | 0.5～1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure. |
| 产品形态 | 溶液 |
| 背景资料 | CASP9 (CASPASE9),also called APAF3,is an initiator caspase,encoded by the CASP9 gene.The CASP9 gene is mapped to chromosome 1p36.3-p36.1 by FISH.CASP9 is identified as a member of the caspase family that participates in caspase-3 activation in vitro.And it also regarded as the most upstream member of the apoptotic protease cascade that is triggered by cytochrome c and dATP.Its genomic coordinates (GRCh37) is 1:15,818,768-15,851,284.The crystal structure of CASP9 is complex with the BIR3 in an inhibitory domain of XIAP at 2.4-angstrom resolution and the CASP9 gene contains 9 exons and spans approximately 35kb of genomic DNA.Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome c and dATP,an event that leads to caspase-9 activation.CASP9 activity increases dramatically upon association with the apoptosome complex.And the majority of Casp9 knockout mice died perinatally with a markedly enlarged and malformed cerebrum caused by reduced apoptosis during brain development. |
| Uniprot ID | P55211 |
| 基因名全称 | Caspase-9 |
| 蛋白名全称 | Caspase-9 (CASP9) |
| 推荐稀释比 | WB,1:500,ECL,Human,Mouse,Rat |
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