产品货号：
Z12679
中文名称：
BUB3抗体
英文名称：
Anti-BUB3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BUB3 Antibody |
| 指标别名 | BUB3;BUB3L;hBUB3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC |
| 基因名称 | BUB3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Bub3(76-90aa DHQLKMHDLNTDQEN),identical to the related rat and mouse sequences. |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BUB3(BUDDING UNINHIBITED BY BENZIMIDAZOLES 3) is a protein that in humans is encoded by the BUB3 gene.And it is mapped on 10q26.13.Bub3 is also a protein involved with the regulation of the Spindle Assembly Checkpoint(SAC);though BUB3 is non-essential in yeast,it is essential in higher eukaryotes.As one of the checkpoint proteins,Bub3 delays the irreversible onset of anaphase through direction of kinetochore localization during prometaphase to achieve biorentation.Bub3 directs the localization of Bub1 at the kinetochore in order to activate the SAC.Bub3 also acts as a regulator in that it affects binding of Mad3 to Mad2.Using deletion analysis,the authors identified a domain of BUB1 that is required both for binding BUB3 and for kinetochore localization of BUB1. |
| Uniprot ID | O43684 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | budding uninhibited by benzimidazoles 3 homolog(yeast) |
| 蛋白名全称 | Mitotic checkpoint protein BUB3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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