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产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > c-Cbl/CBL抗体
c-Cbl/CBL抗体图片
产品货号:
Z12678
中文名称:
c-Cbl/CBL抗体
英文名称:
Anti-c-Cbl/CBL Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-c-Cbl/CBL Antibody
指标别名C CBL;CBL;CBL2;c-Cbl;Proto oncogene c Cbl;RING finger protein 55;RNF55
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称CBL
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human CBL(863-877aa NLMSQGYSYQDIQKA),identical to the related rat and mouse sequences.
实际分子量120KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料CBL(Cbl proto-oncogene) is also known as C-CBL,RNF55,CBL2 and E3 ubiquitin protein ligase.Wei et al.(1990) mapped the CBL gene to chromosome 11q23.3-qter by molecular characterization of the breakpoints in 2 somatic cell hybrids.The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome.This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes(E2) to specific substrates.This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation.As such it functions as a negative regulator of many signal transduction pathways.This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia.Mutations in this gene are also the cause of Noonan syndrome-like disorder.
Uniprot IDP22681
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称Cbl proto-oncogene,E3 ubiquitin protein ligase
蛋白名全称E3 ubiquitin-protein ligase CBL
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:c-Cbl/CBL抗体c-Cbl抗体CBL多抗Anti-c-Cbl/CBL Antibody
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