产品货号：
Z12581
中文名称：
CBS抗体
英文名称：
Anti-CBS Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CBS Antibody |
| 指标别名 | Beta thionase;CBS;cystathionine beta synthase;HIP4;Serine sulfhydrase |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | CBS |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CBS recombinant protein (Position:A331-K551).Human CBS shares 83% amino acid (aa) sequence identity with both mouse and rat CBS. |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cystathionine-β-synthase,also known as CBS,is an enzyme that in humans is encoded by the CBS gene.It is mapped to 21q22.3 and contains 23 exons,ranging in size from 42 to 299bp.CBS catalyzes the first step of the transsulfuration pathway,from homocysteine to cystathionine.It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet).This enzyme belongs to the family of lyases,to be specific,the hydro-lyases,which cleave carbon-oxygen bonds.CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains.The CBS gene is the most common locus for mutations associated with homocystinuria. |
| Uniprot ID | P35520 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cystathionine-beta-synthase |
| 蛋白名全称 | Cystathionine beta-synthase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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