产品货号：
Z12570
中文名称：
CBLC抗体
英文名称：
Anti-CBLC Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CBLC Antibody |
| 指标别名 | E3 ubiquitin-protein ligase CBL-C;6.3.2.-;RING finger protein 57;SH3-binding protein CBL-3;SH3-binding protein CBL-C;Signal transduction protein CBL-C;CBLC;CBL3;RNF57 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC,IP,WB |
| 基因名称 | CBLC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-Terminal portion of Human Cbl-c. |
| 计算分子量 | 52kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against human Cbl-c protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest that this antibody would react with Cbl-c from human and chimpanzee sources.Expect partial reactivity against mouse and rat sources of Cbl-c as~83% sequence homology is on record for the immunogen sequence.Reactivity with Cbl-c from other sources has not been determined.No reactivity is expected with Cbl-a or Cbl-b. |
| 浓度 | 1.2mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.Cbl-c is also known as signal transduction protein CBL-C,SH3-binding protein CBL-C,CBL-3,and RING finger protein 57.Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation.Cbl-c (a.k.a.Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed).Cbl-c,like the other mammalian Cbl proteins,can ubiquitinate the activated EGFR and target it for degradation.Cbl-c knock out mice show no obvious phenotype.Thus,the physiological role of Cbl-c is not known. |
| Uniprot ID | Q9ULV8 |
| 基因名全称 | E3 ubiquitin-protein ligase CBL-C |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IHC:1:500 - 1:3,000 IP:User Optimized WB:1:500 - 1:3,000 |
相关搜索：CBLC抗体，CBLC多抗，Anti-CBLC Antibody