产品货号：
Z12535
中文名称：
Caspase 5/CASP5抗体
英文名称：
Anti-Caspase 5/CASP5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caspase 5/CASP5 Antibody |
| 指标别名 | caspase 5;Caspase-5;ICE(rel)III;ICEREL-III;ICH-3;Caspase5;CASP5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,IHC,ELISA |
| 基因名称 | CASP5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Caspase-5/CASP5 recombinant protein (Position:D137-N434). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits,large and small,that dimerize to form the active enzyme.Overexpression of the active form of this enzyme induces apoptosis in fibroblasts.Max,a central component of the Myc/Max/Mad transcription regulation network important for cell growth,differentiation,and apoptosis,is cleaved by this protein;this process requires Fas-mediated dephosphorylation of Max.The expression of this gene is regulated by interferon-gamma and lipopolysaccharide.Alternatively spliced transcript variants have been identified for this gene. |
| Uniprot ID | P51878 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | caspase 5 |
| 蛋白名全称 | Caspase-5 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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