产品货号:
Z12462
中文名称:
Calpastatin/CAST抗体
英文名称:
Anti-Calpastatin/CAST Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Calpastatin/CAST Antibody |
指标别名 | BS 17;Calpain inhibitor;calpastatin;CAST;Sperm BS 17 component;Xiap1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,IHC-F,ICC/IF,FCM |
基因名称 | CAST |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Calpastatin (275-310aa QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR),different from the related mouse sequence by fifteen amino acids,and from the related rat sequence by eleven amino acids. |
实际分子量 | 76KD,120KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Calpastatin is a protein that in humans is encoded by the CAST gene.It is mapped to 5q15.The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor.It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4),and it is involved in the proteolysis of amyloid precursor protein.The calpain/calpastatin system is involved in numerous membrane fusion events,such as neural vesicle exocytosis and platelet and red-cell aggregation.The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins.Alternatively spliced transcript variants encoding different isoforms have been described. |
Uniprot ID | P20810 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunohistochemistry in frozen section 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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