产品货号:
Z12276
中文名称:
CARD10抗体
英文名称:
Anti-CARD10 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-CARD10 Antibody |
| 指标别名 | BIMP1;CARMA3;Caspase recruitment domain-containing protein 10;CARD-containing MAGUK protein 3;Carma 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | CARD10 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.The immunogen is located within the last 50 amino acids of CARD10. |
| 计算分子量 | 116kDa |
| 成分 | CARD10 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CARD10 Antibody is immunoaffinity purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD),death effector domain (DED),and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases,Apaf-1,CARD4,IAPs,RICK,ARC,RAIDD,Bcl-10,and ASC.A novel CARD-containing protein was recently identified and designated CARD10.This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules.CARD 10 interacts with Bcl-10,a Bcl protein that promotes apoptosis,caspase-9 maturation and activation of NF-百B.CARD 10 and the related protein CARMA1 also associate with NEMO,the regulatory subunit of the I百K complex,demonstrating its importance in the regulation of NF-百B transcription factor activation. |
| Uniprot ID | Q9BWT7 |
| 基因名全称 | Caspase recruitment domain family,member 10 |
| 蛋白名全称 | Caspase recruitment domain family,member 10 |
| 推荐稀释比 | CARD10 antibody can be used for detection of CARD10 by Western blot at 5μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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