产品货号：
Z12203
中文名称：
C9orf72抗体
英文名称：
Anti-C9orf72 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-C9orf72 Antibody |
| 指标别名 | C9orf72,C9RANT,RP11 27J8.2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM |
| 基因名称 | C9ORF72 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human C9ORF72 (APKTEQVLLSDGEITFLANHTLNGEILR). |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | C9orf72 (chromosome 9 open reading frame 72) is a protein which in humans is encoded by the gene C9orf72.It is mapped to 9p21.2.The protein encoded by this gene plays an important role in the regulation of endosomal trafficking,and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport.Expansion of a GGGGCC repeat from 2～22 copies to 700～1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID:21944778,21944779).Studies suggest that hexanucleotide expansions could result in the selective stabilization of repeat-containing pre-mRNA,and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID:23393093).Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | Q96LT7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：C9orf72抗体，C9orf72多抗，Anti-C9orf72 Antibody