产品货号：
Z11961
中文名称：
Beta Amyloid/APP抗体
英文名称：
Anti-Beta Amyloid/APP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Beta Amyloid/APP Antibody |
| 指标别名 | ABETA;ABPP;amyloid beta 1-42;Amyloid beta A4 protein;amyloid P;amyloid precursor protein;Amyloid-beta precursor protein;Amyloid-beta protein 40;Amyloid-beta protein 42;APP;APPI;Aβ1-42;beta Amyloid |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC/IF,FCM |
| 基因名称 | APP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human APP(672-713aa DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA),different from the related mouse and rat sequences by three amino acids. |
| 实际分子量 | 87～120KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | beta Amyloid,also called Abeta or Abeta,denotes peptides of 36–43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients.It is mapped to 19q13.12.Several potential activities have been discovered for beta Amyloid,including activation of kinase enzymes,functioning as atranscription factor,and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity).Moreover,monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity. |
| Uniprot ID | P05067 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | amyloid beta (A4) precursor protein |
| 蛋白名全称 | Amyloid beta A4 protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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