产品货号：
Z11944
中文名称：
Beta Amyloid/APP抗体
英文名称：
Anti-Beta Amyloid/APP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Beta Amyloid/APP Antibody |
| 指标别名 | ABETA;ABPP;amyloid beta 1-42;Amyloid beta A4 protein;amyloid P;amyloid precursor protein;Amyloid-beta precursor protein;Amyloid-beta protein 40;Amyloid-beta protein 42;APP;APPI;Aβ1-42;beta Amyloid |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | APP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human APP/C99(DAEFRHDSGYEVHHQKLVFFAEDVGSNK). |
| 实际分子量 | 87～120KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons.It is mapped to 21q21.3.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation,while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.In addition,two of the peptides are antimicrobial peptides,having been shown to have bacteriocidal and antifungal activities.Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Uniprot ID | P05067 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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