产品货号:
Z11892
中文名称:
BLNK抗体
英文名称:
Anti-BLNK Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BLNK Antibody |
指标别名 | B cell linker;B cell linker protein;BASH;BLNK;BLNK S;Cytoplasmic adapter protein;LY57;SLP 65;SLP65 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC,ELISA |
基因名称 | BLNK |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human BLNK around the non-phosphorylation site of Y96. |
计算分子量 | 50KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | The B-cell linker protein is encoded by the BLNK gene and is an adaptor protein also known as SLP-65,BASH,and BCA.This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways,thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells,a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.Alternatively spliced transcript variants have been found for this gene. |
Uniprot ID | Q8WV28 |
基因名全称 | B-cell linker protein |
蛋白名全称 | B-cell linker protein |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:20000 |
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