产品货号：
Z11889
中文名称：
BMF抗体
英文名称：
Anti-BMF Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BMF Antibody |
| 指标别名 | BMF |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | BMF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Bmf antibody was raised with a synthetic peptide corresponding to 14 amino acids near the carboxy terminus of human Bmf.The immunogen is located within the last 50 amino acids of Bmf. |
| 计算分子量 | 21kDa |
| 成分 | Bmf Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bmf Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases and development.Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3-only proteins,including Bad,Bid,Bik,Hrk,Bim,Noxa,and PUMA,form a growing subclass of the Bcl-2 family.A novel BH3-only protein was recently identified in human and mouse and designated Bmf (for Bcl-2-modifing factor).The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis.In healthy cells,Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell's actin cytoskeleton.Disruption of the actin cytoskeleton,either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix,triggers release and activation of Bmf,initiating the downstream apoptotic program.Bmf is constitutively expressed in many tissues. |
| Uniprot ID | Q96LC9 |
| 基因名全称 | Bcl2 modifying factor |
| 蛋白名全称 | Bcl2 modifying factor |
| 推荐稀释比 | Bmf antibody can be used for detection of Bmf by Western blot at 2.5 and 5μg/mL.A band at approximately 25kDa can be detected.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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