产品货号：
Z11887
中文名称：
BIN1抗体
英文名称：
Anti-BIN1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BIN1 Antibody |
| 指标别名 | AMPH2;Amphiphysin II;Amphiphysin like protein;AMPHL;BIN1;bridging integrator 1;SH3P9 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | BIN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human BIN1 recombinant protein (Position:E45-P593). |
| 实际分子量 | 65～80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Myc box-dependent-interacting protein 1,also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene.This gene encodes several isoforms of a nucleocytoplasmic adaptor protein,one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor.Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin,synaptojanin,endophilin,and clathrin.Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process.Studies in mouse suggest that this gene plays an important role in cardiac muscle development.Alternate splicing of the gene results in several transcript variants encoding different isoforms.Aberrant splice variants expressed in tumor cell lines have also been described. |
| Uniprot ID | O00499 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | bridging integrator 1 |
| 蛋白名全称 | Myc box-dependent-interacting protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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