产品货号：
Z11881
中文名称：
BMPR1B抗体
英文名称：
Anti-BMPR1B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BMPR1B Antibody |
| 指标别名 | bone morphogenetic protein receptor type 1B;ALK-6;ALK6;AMDD;BDA1D;BDA2;CDw293;BMPR1B |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | BMPR1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human BMPR1B recombinant protein (Position:K14-Q184).Human BMPR1B shares 97.1% amino acid (aa) sequence identity with mouse BMPR1B. |
| 实际分子量 | 57KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BMPR1B (Bone Morphogenetic Protein Receptor Type IB),also known as ALK6,is a protein which in humans is encoded by the BMPR1B gene.BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases.The ligands of this receptor are BMPs,which are members of the TGF-beta superfamily.BMPs are involved in endochondral bone formation and embryogenesis.These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors:type I receptors of about 50～55kD and type II receptors of about 70～80kD.Type II receptors bind ligands in the absence of type I receptors,but they require their respective type I receptors for signaling,whereas type I receptors require their respective type II receptors for ligand binding.By analysis of a monochromosome hybrid mapping panel and by FISH,Astrom et al.(1999) mapped the BMPR1B gene to chromosome 4q22-q24.Ide et al.(1997) compared BMP receptor expression in normal and cancerous prostate tissues.While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues,BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue. |
| Uniprot ID | O00238 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | bone morphogenetic protein receptor,type IB |
| 蛋白名全称 | Bone morphogenetic protein receptor type-1B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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