产品货号：
Z11725
中文名称：
B7-2/CD86抗体
英文名称：
Anti-B7-2/CD86 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-B7-2/CD86 Antibody |
| 指标别名 | Activation B7 2 antigen;B7 2;B70;BU63;CD28LG2;CD86;CD86 molecule;FUN 1;LAB72 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CD86 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CD86 antibody was raised against a peptide corresponding to 17 amino acids near the center of human CD86.The immunogen is located within amino acids 160 - 210 of CD86. |
| 计算分子量 | 35kDa |
| 成分 | CD86 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CD86 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CD86,also known as B7-2,is a type I membrane protein that is a member of the immunoglobulin superfamily.Like the related protein CD80,this protein is expressed by antigen-presenting cells,and is the ligand for two proteins at the cell surface of T cells,CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production.CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response (1).Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia (ALL),suggesting that this pathway may be an attractive target for future cancer immunotherapy (2). |
| Uniprot ID | P42082 |
| 基因名全称 | CD86 molecule |
| 蛋白名全称 | CD86 molecule |
| 推荐稀释比 | CD86 antibody can be used for Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry at 2μg/mL.For Immunoflorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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