产品货号:
Z11656
中文名称:
BANP抗体
英文名称:
Anti-BANP Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BANP Antibody |
指标别名 | BANP,BEND1,Protein BANP,SMAR1,SMARBP1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BANP |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | BANP antibody was raised against a 14 amino acid synthetic peptide near the center of human BANP.The immunogen is located within amino acids 300 - 350 of BANP. |
计算分子量 | 56kDa |
成分 | BANP Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | BANP Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen.BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest.p53 in turn binds to upstream elements of the BANP promoter,thereby forming a feedback loop.BANP is down-regulated in advanced stages of human breast cancer,and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling.Furthermore,BANP can modulate NF-百B transactivation and can inhibit tumorigenesis by regulating NF-百B target genes.Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix. |
Uniprot ID | Q8N9N5 |
基因名全称 | BTG3 associated nuclear protein |
蛋白名全称 | BTG3 associated nuclear protein |
推荐稀释比 | BANP antibody can be used for detection of BANP by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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