产品货号:
Z11609
中文名称:
ATG4B抗体
英文名称:
Anti-ATG4B Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG4B Antibody |
指标别名 | APG4B;ATG4B;AUTL1;Autophagin 1;Cysteine protease ATG4B;hAPG4B;KIAA0943 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ATG4B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ATG4B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ATG4B.The immunogen is located within the last 50 amino acids of ATG4B. |
计算分子量 | 44kDa |
成分 | ATG4B antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ATG4B antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2).ATG4B,also known as AUTL1,is one of four mammalian orthologs of the yeast ATG4 protein;all four are cysteine proteases (3).ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes.In mammals,each ATG4 homolog shows a selective preference for the ATG8 homologs (4).ATG4B has been found to be a novel protective protein in inflammatory colitis (5). |
Uniprot ID | Q9Y4P1 |
基因名全称 | Autophagy related 4B,cysteine peptidase |
蛋白名全称 | Autophagy related 4B,cysteine peptidase |
推荐稀释比 | ATG4B antibody can be used for detection of ATG4B by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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