产品货号：
Z11584
中文名称：
B4GALT1抗体
英文名称：
Anti-B4GALT1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-B4GALT1 Antibody |
| 指标别名 | Beta-1;4-galactosyltransferase 1;Beta-1;4-GalTase 1;Beta4Gal-T1;b4Gal-T1;2.4.1.-;UDP-Gal:beta-GlcNAc beta-1;4-galactosyltransferase 1;UDP-galactose:beta-N-acetylglucosamine beta-1;4-galactosyltransferase 1;Lactose synthase A protein;2.4.1.22;N-acetyllactosamine synthase;2.4.1.90;Nal synthase;Beta-N-acetylglucosaminylglycopeptide beta-1;4-galactosyltransferase;2.4.1.38;Beta-N-acetylglucosaminyl-glycolipid beta-1;4-galactosyltransferase;2.4.1.-;Processed beta-1;4-galactosyltransferase 1;B4GALT1;GGTB2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | B4GALT1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human beta-1,4-Gal-T1. |
| 计算分子量 | 44KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Beta-1,4-galactosyltransferase 1 is an enzyme that in humans is encoded by the B4GALT1 gene.It is mapped to 9p21.1.This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes.They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose;all transfer galactose in a beta1,4 linkage to similar acceptor sugars:GlcNAc,Glc,and Xyl.Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.As type II membrane proteins,they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor.By sequence similarity,the beta4GalTs form four groups:beta4GalT1 and beta4GalT2,beta4GalT3 and beta4GalT4,beta4GalT5 and beta4GalT6,and beta4GalT7.This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis.For the first activity,the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains.The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose.The two enzymatic forms result from alternate transcription initiation sites and post-translational processing.Two transcripts,which differ only at the 5' end,with approximate lengths of 4.1kb and 3.9kb encode the same protein.The longer transcript encodes the type II membrane-bound,trans-Golgi resident protein involved in glycoconjugate biosynthesis.The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase. |
| Uniprot ID | P15291 |
| 基因名全称 | Beta-1,4-galactosyltransferase 1 |
| 蛋白名全称 | Beta-1,4-galactosyltransferase 1 |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:100～1:300 ELISA 1:20000 |
相关搜索：B4GALT1抗体，B4GALT1多抗，Anti-B4GALT1 Antibody