产品货号：
Z11563
中文名称：
BAK/BAK1抗体
英文名称：
Anti-BAK/BAK1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAK/BAK1 Antibody |
| 指标别名 | Apoptosis regulator BAK;BAK;BAK LIKE;BAK1;CDN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,IF,IHC,WB |
| 基因名称 | BAK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human Bak |
| 计算分子量 | 23KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | BAK,officially called Bcl2 antagonist killer,is a protein that in humans,encoded by the BAK gene.The BAK protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis.BAK gene spans 7.6kb and contains 6 exons.By Southern blot analysis of genomic DNA from human/rodent somatic cell hybrids,BAK gene is localized to chromosome 6.This protein localizes to mitochondria,and functions to induce apoptosis.It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel,which leads to a loss in membrane potential and the release of cytochrome.This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Uniprot ID | Q16611 |
| 基因名全称 | Bcl-2 homologous antagonist/killer |
| 蛋白名全称 | Bcl-2 homologous antagonist/killer |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:100～1:300 IF 1:200～1:1000 ELISA 1:10000 |
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