产品货号：
Z11535
中文名称：
BCRP/ABCG2抗体
英文名称：
Anti-BCRP/ABCG2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCRP/ABCG2 Antibody |
| 指标别名 | ABC15;ABCG2;ABCP;BCRP;ABCG2;BMDP;CD338;CDw338;EST157481;MRX;MXR;MXR1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | ABCG2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminal of human ABCG2(742-755aa,TIAYLKLLFLKKYS),identical to the related mouse and rat sequence. |
| 实际分子量 | 65～80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ABCG2(Atp-binding cassette,subfamily g,member 2) also known as ABCP,BCRP or MRX,is a protein that in humans is encoded by the ABCG2 gene.The ABCG2 gene encodes a membrane transporter belonging to the ATP-binding cassette(ABC) superfamily of membrane transporters,which are involved in the trafficking of biologic molecules across cell membranes.The ABCG2 protein is also a high capacity transporter for uric acid excretion in the kidney,liver,and gut.The ABCG2 gene is mapped on 4q22.1.In vitro assays of isolated membrane preparations revealed a high-capacity,vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.Ozvegy et al.(2001)°Concluded that ABCG2 is likely functioning as a homodimer or homooligomer in this expression system since it is unlikely that putative Sf9 transport partners would be overexpressed at similarly high levels.Abcg2 transports pheophorbide-a,which occurs in various plant-derived foods and food supplements and is highly efficient in limiting its uptake from ingested food.ABCG2 is a major factor in the concentrative transfer of drugs,carcinogens,and dietary toxins to the milk of mice,cows,and humans. |
| Uniprot ID | Q7TMS5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ATP-binding cassette,sub-family G(WHITE),member 2 |
| 蛋白名全称 | ATP-binding cassette sub-family G member 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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