产品货号：
Z11531
中文名称：
Beclin 2/BECN2抗体
英文名称：
Anti-Beclin 2/BECN2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Beclin 2/BECN2 Antibody |
| 指标别名 | BECN2,BECN1L1,Beclin-1-like protein 1,Beclin 1 autophagy related pseudogene 1,BECN1P1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | BECN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Beclin 2 antibody was raised against a 16 amino acid peptide near the amino terminus of human Beclin 2.The immunogen is located within amino acids 30 - 80 of Beclin 2. |
| 计算分子量 | 48kDa |
| 成分 | Beclin 2 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Beclin 2 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2).Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3).Like Beclin 1,Beclin 2 interacts with Bcl-2 and class III PI3K complex components.However,Beclin 2 functions in an additional lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (3).Beclin 2 is also required for agonist-induced lysosome-mediated degradation of EGFR in lung cancer cells,suggesting that it may also play a role in regulating other intracellular signaling pathways (4). |
| Uniprot ID | A8MW95 |
| 基因名全称 | Beclin 1,autophagy related,pseudogene 1 |
| 蛋白名全称 | Beclin 1,autophagy related,pseudogene 1 |
| 推荐稀释比 | Beclin 2 antibody can be used for detection of Beclin 2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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