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产品目录

Beclin 1/BECN1抗体图片
产品货号:
Z11522
中文名称:
Beclin 1/BECN1抗体
英文名称:
Anti-Beclin 1/BECN1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Beclin 1/BECN1 Antibody
指标别名ATG6;Beclin 1;beclin 1;autophagy related;beclin1;BECN1;GT197;Protein GT197;VPS30;Beclin-1
克隆性Polyclonal
检验物种human,mouse
应用范围ELISA,WB,ICC,IF
基因名称BECN1
抗体来源Rabbit
抗体类型IgG
免疫原Beclin-1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Beclin-1.The immunogen is located within the last 50 amino acids of Beclin-1.
计算分子量52kDa
成分Beclin-1 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式Beclin-1 Antibody is affinity chromatography purified via peptide column.
浓度1mg/mL
产品形态溶液
保存条件Beclin-1 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures.
背景资料Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.Beclin-1,a coiled-coil Bcl-2-interacting protein homologous to the yeast autophagy gene apg6,is a mammalian autophagy gene that can inhibit tumorigenesis and is expressed at reduced levels in human breast carcinoma,suggesting that defects in autophagy proteins may contribute to the development or progression of tumors.Bcl-2 can bind to Beclin-1 and inhibit Beclin-1-dependent autophagy in yeast and mammalian cells,suggesting that Bcl-2 functions as an anti-autophagy protein as well as an anti-apoptotic protein,which helps maintain autophagy at levels that are more compatible with cell survival rather than cell death.
Uniprot IDQ14457
基因名全称Beclin 1,autophagy related
蛋白名全称Beclin 1,autophagy related
推荐稀释比Beclin-1 antibody can be used for the detection of Beclin-1 by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

相关搜索:Beclin 1/BECN1抗体Beclin 1抗体BECN1多抗Anti-Beclin 1/BECN1 Antibody
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