产品货号:
Z11472
中文名称:
BAD抗体
英文名称:
Anti-BAD Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BAD Antibody |
指标别名 | BAD;BBC2;BBC6 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BAD |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.The immunogen is located within amino acids 90 - 140 of BAD. |
计算分子量 | 18kDa |
成分 | BAD Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | BAD Antibody is Ion exchange chromatography purified. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins,such as Bax,Bid,and Bik,form a growing subclass of the Bcl-2 family.Another such protein is the Bcl-2-antagonist of cell death (Bad).Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL,thereby preventing them from binding with Bax.Bad activity is regulated by its phosphorylation;it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival,whereas JNK-induced phosphorylation promotes the apoptotic role of Bad. |
Uniprot ID | Q92934 |
基因名全称 | BCL2-associated agonist of cell death |
蛋白名全称 | BCL2-associated agonist of cell death |
推荐稀释比 | Bad antibody can be used for detection of Bad by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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