产品货号：
Z11456
中文名称：
ATOH8抗体
英文名称：
Anti-ATOH8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATOH8 Antibody |
| 指标别名 | HATH6,bHLHa21,ATH6,BHLHA21,Protein atonal homolog 8,Class A basic helix-loop-helix protein 21 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | ATOH8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATOH8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ATOH8.The immunogen is located within the last 50 amino acids of ATOH8. |
| 计算分子量 | 35kDa |
| 成分 | ATOH8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATOH8 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates.ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43～57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors.In the mouse,ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development.Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3.It is indispensable for early embryonic development,suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes. |
| Uniprot ID | Q96SQ7 |
| 基因名全称 | Atonal homolog 8 (Drosophila) |
| 蛋白名全称 | Atonal homolog 8 (Drosophila) |
| 推荐稀释比 | ATOH8 antibody can be used for detection of ATOH8 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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