产品货号:
Z11378
中文名称:
ATG2B抗体
英文名称:
Anti-ATG2B Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG2B Antibody |
指标别名 | ATG2B,C14orf103 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IF |
基因名称 | ATG2B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ATG2B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATG2B.The immunogen is located within amino acids 450 - 500 of ATG2B. |
计算分子量 | 233kDa |
成分 | ATG2B Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ATG2B Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.Another member of the autophagy family of proteins is ATG2B,one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas,suggesting that deregulating the autophagy process may contribute to cancer development. |
Uniprot ID | Q96BY7 |
基因名全称 | Autophagy-related protein 2 homolog B |
蛋白名全称 | Autophagy-related protein 2 homolog B |
推荐稀释比 | ATG2B antibody can be used for detection of ATG2B by Western blot at 1 ~ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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