产品货号:
Z11297
中文名称:
APC11/ANAPC11抗体
英文名称:
Anti-APC11/ANAPC11 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-APC11/ANAPC11 Antibody |
指标别名 | APC11;Apc11p;HSPC214;MGC882 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IHC,WB |
基因名称 | ANAPC11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH. |
成分 | 0.01% (w/v) Sodium Azide |
纯化方式 | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.This product reacts with human and mouse APC11.Cross-reactivity may also occur with APC11 from other sources.Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2. |
浓度 | 85mg/mL by Refractometry |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | APC11 is also known as Anaphase promoting complex subunit 11,APC11,Cyclosome subunit 11,Hepatocellular carcinoma associated RING finger protein,and HSPC214.APC11 is a component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex.APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2.APC11 shows both a cytoplasmic and nuclear localization.APC11 is expressed at high levels in skeletal muscle and heart;in moderate levels in brain,kidney,and liver;and at low levels in colon,thymus,spleen,small intestine,placenta,lung and peripheral blood leukocyte.APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated. |
Uniprot ID | Q9NYG5 |
推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:User Optimized IP:User Optimized WB:1:500 - 1:1,000 |
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