产品货号：
Z11214
中文名称：
ARMETL1/CDNF抗体
英文名称：
Anti-ARMETL1/CDNF Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARMETL1/CDNF Antibody |
| 指标别名 | ARMET like protein 1;ARMETL1;cdnf |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC |
| 基因名称 | CDNF |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthetic peptide from human protein at AA range:31-80. |
| 计算分子量 | 21KD |
| 成分 | PBS,pH7.4,containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Cerebral dopamine neurotrophic factor also known as ARMET-like protein 1 or is a protein that in humans that is encoded by the CDNF gene.CDNF and MANF are secreted proteins with 8 conserved cysteine residues,which predict a unique protein fold and define an evolutionarily conserved protein family.The human CDNF mRNA encodes a 187-amino acid protein with a predicted signal peptide and apparently no prosequence.The predicted secondary structure,like that of MANF,is dominated by alpha-helices.Human CDNF shares 59% amino acid identity with human MANF,and 49% and 46% identity with D.melanogaster and C.elegans Manf proteins,respectively.RT-PCR of mouse brain detected Cdnf transcripts in embryonic and postnatal stages,and in adult brain regions,including the striatum.In the midbrain,Cdnf mRNA was expressed from embryonic stages to the adult.High levels of Cdnf mRNA were observed in adult mouse heart,skeletal muscle,and testis.In agreement with the results from mouse,wide expression of CDNF transcripts was detected in human brain and nonneuronal tissues.Interestingly,levels of CDNF transcripts were relatively high in the corpus callosum and optic nerve,which are devoid of neuronal cell bodies and contain mostly axonal projections and oligodendrocytes.At postnatal stage P10 of the mouse brain,Cdnf staining was most intense in the hippocampus and thalamus.Cdnf signal was also detected in striatum and substantia nigra. |
| Uniprot ID | Q49AH0 |
| 基因名全称 | Cerebral dopamine neurotrophic factor |
| 推荐稀释比 | IHC-P,1:50～300 |
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