产品货号:
Z11181
中文名称:
ASPH抗体
英文名称:
Anti-ASPH Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ASPH Antibody |
指标别名 | AAH;ASP beta hydroxylase;aspartate beta hydroxylase;ASPH;BAH;CASQ2BP1;HAAH;JCTN;junctin |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC,FCM |
基因名称 | ASPH |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ASPH (726-758aa EVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI),identical to the related mouse sequence. |
实际分子量 | 86KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ASPH is also known as Aspartyl/asparaginyl beta-hydroxylase.This gene is thought to play an important role in calcium homeostasis.And the gene is expressed from two promoters and undergoes extensive alternative splicing.The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties.The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins,including protein C,coagulation factors VII,IX,and X,and the complement factors C1R and C1S.Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain,and some have been localized to the endoplasmic and sarcoplasmic reticulum.Some of these isoforms are found in complexes with calsequestrin,triadin,and the ryanodine receptor,and have been shown to regulate calcium release from the sarcoplasmic reticulum.Some isoforms have been implicated in metastasis. |
Uniprot ID | Q12797 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | aspartate beta-hydroxylase |
蛋白名全称 | Aspartyl/asparaginyl beta-hydroxylase |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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