产品货号：
Z11150
中文名称：
ARHGEF4抗体
英文名称：
Anti-ARHGEF4 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARHGEF4 Antibody |
| 指标别名 | ARHGEF4;ASEF;ASEF1;GEF4;KIAA1112;STM6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ELISA |
| 基因名称 | ARHGEF4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human ARHG4 protein. |
| 计算分子量 | 79KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | ARHG4 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | ARHGEF4 (Rho guanine nucleotide exchange factor 4),also known as ASEF 1 (adenomatous polyposis coli每;stimulated guanine nucleotide exchange factor 1) is an approximately 80kDa cytoplasmic protein important for growth factor-mediated regulation of cell morphology and migration.Besides N-terminal adenomatous polyposis coli (APC)-binding region (ABR) it contains Dbl homology (DH),pleckstrin homology (PH) and SH3 domains.The SH3 domain inhibits GEF activity of ARHGEF4 by intramolecular interaction with the DH domain,whereas binding of APC stimulates the GEF activity.Activated ARHGEF4 stimulates the small GTPase Cdc42,which leads to decreased cell-cell adherence and enhanced cell migration. |
| Uniprot ID | Q9NR80 |
| 基因名全称 | Rho guanine nucleotide exchange factor 4 |
| 蛋白名全称 | Rho guanine nucleotide exchange factor 4 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
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