产品货号：
Z10837
中文名称：
(Mouse) EED抗体
英文名称：
Anti-(Mouse) EED Antibody (Center)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-(Mouse) EED Antibody (Center) |
| 指标别名 | EED;embryonic ectoderm development;HEED;Polycomb protein EED;WAIT 1;WAIT1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC |
| 基因名称 | Eed |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This mouse Eed antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 269-303 amino acids from the Central region of mouse Eed. |
| 计算分子量 | 50kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Polycomb group (PcG) protein.Component of the PRC2/EED- EZH2 complex,which methylates 'Lys-9' and 'Lys-27' of histone H3,leading to transcriptional repression of the affected target gene.Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27',whereas H3 'Lys-27' recognition has the opposite effect,enabling the propagation of this repressive mark (By similarity).The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases,thereby linking two epigenetic repression systems (By similarity).Genes repressed by the PRC2/EED-EZH2 complex include HOXA7,HOXB6 and HOXC8.Plays a role in X chromosome inactivation (XCI),in which one of the two X chromosomes in female mammals is transcriptionally silenced to equalize X-linked gene dosage with XY males.Required for stable maintenance of XCI in both embryonic and extraembryonic tissues.May prevent transcriptional activation of facultative heterochromatin during differentiation.Required for development of secondary trophoblast giant cells during placental development.May regulate hippocampal synaptic plasticity in the developing brain. |
| Uniprot ID | Q921E6 |
相关搜索：(Mouse) EED抗体，(Mouse) EED(Center)多抗，Anti-(Mouse) EED Antibody (Center)