产品货号：
Z10835
中文名称：
(Mouse) DNMT1抗体
英文名称：
Anti-(Mouse) DNMT1 Antibody (Center)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-(Mouse) DNMT1 Antibody (Center) |
| 指标别名 | AIM;CXXC9;DNA MTase HsaI;DNMT;DNMT1;MCMT |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,IF |
| 基因名称 | Dnmt1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This MouseDnmt1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 881-914 amino acids from the Central region of mouse Dnmt1. |
| 计算分子量 | 183kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Methylates CpG residues.Preferentially methylates hemimethylated DNA.Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand,that is essential for epigenetic inheritance.Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication.It is responsible for maintaining methylation patterns established in development.DNA methylation is coordinated with methylation of histones.Mediates transcriptional repression by direct binding to HDAC2.In association with DNMT3B and via the recruitment of CTCFL/BORIS,involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. |
| Uniprot ID | P13864 |
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