产品货号：
Z10618
中文名称：
AKT2抗体
英文名称：
Anti-AKT2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKT2 Antibody |
| 指标别名 | AKT2;PKB beta;PKBB;PKBBETA;PRKBB;Protein kinase Akt 2;Protein kinase B beta;RAC BETA;RAC PK beta |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | AKT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human AKT2(454-481aa DRYDSLGLLELDQRTHFPQFSYSASIRE),different from the related mouse sequence by two amino acids,and from the related rat sequence by one amino acid. |
| 实际分子量 | 56KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains.This gene is mapped to 19q13.2.AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1,AKT2 and AKT3) called the AKT kinase,and which regulate many processes including metabolism,proliferation,cell survival,growth and angiogenesis.AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake.AKT2 is also specifically involved in skeletal muscle differentiation,one of its substrates in this process being ANKRD2.Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. |
| Uniprot ID | P31751 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | v-akt murine thymoma viral oncogene homolog 2 |
| 蛋白名全称 | RAC-beta serine/threonine-protein kinase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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