产品货号：
Z10608
中文名称：
AKR1C3抗体
英文名称：
Anti-AKR1C3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKR1C3 Antibody |
| 指标别名 | 17 beta HSD 5;3 alpha HSD type 2;3 alpha HSD type II;brain;AKR1C3;DD 3;DD3;DDX;Dihydrodiol dehydrogenase 3;HA1753;HAKRB;HAKRe;hluPGFS;HSD17B5;Indanol dehydrogenase;KIAA0119;PGFS;Prostaglandin F synthase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM |
| 基因名称 | AKR1C3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human AKR1C3 (AEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY). |
| 实际分子量 | 37KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Aldo-keto reductase family 1 member C3 (AKR1C3),also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5,HSD17B5) is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene.This gene encodes a member of the aldo/keto reductase superfamily,which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate specificity.This enzyme catalyzes the reduction of prostaglandin (PG) D2,PGH2 and phenanthrenequinone (PQ),and the oxidation of 9alpha,11beta-PGF2 to PGD2.It may play an important role in the pathogenesis of allergic diseases such as asthma,and may also have a role in controlling cell growth and/or differentiation.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.Three transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P42330 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Aldo-keto reductase family 1 member C3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells |
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