产品货号：
Z10602
中文名称：
AKT1/2/3抗体
英文名称：
Anti-AKT1/2/3 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKT1/2/3 Antibody |
| 指标别名 | AKT;AKT1;PKB;PKB ALPHA;PRKBA;Protein kinase B;Proto oncogene c Akt;RAC;RAC ALPHA;RAC PK alpha;AKT2;PKB beta;PKBB;PKBBETA;PRKBB;Protein kinase Akt 2;Protein kinase B beta;RAC BETA;RAC PK beta;AKT3;PKB GAMMA;PKBG;PRKBG;Protein kinase Akt 3;Protein kinase B gamma;RAC gamma;RAC PK gamma;STK 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | AKT1/AKT2/AKT3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-AKT Pan Reactive Antibody was produced in rabbits by repeated immunizations with a cocktail containing recombinant human AKT1,AKT2,and AKT3 protein isoforms. |
| 成分 | 0.02M Potassium Phosphate,0.5M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | AKT Antibody reacts with the AKT from human tissues.Anti-AKT antibody was purified from monospecific antiserum by Protein A chromatography.Based on sequence we expect this antibody to react as well with rat,mouse,and chicken AKT. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308.AKT is a cytoplasmic protein also known as AKT1,Protein Kinase B (PKB) and rac (related to A and C kinases).AKT is a key regulator of many signal transduction pathways.AKT Exhibits tight control over cell proliferation and cell viability.Overexpression or inappropriate activation of AKT is noted in many types of cancer.AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors,cytokines and insulin).PI 3-kinase recruits AKT to the membrane,where it is activated by PDK1 phosphorylation.Once phosphorylated,AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.AKT has two main roles:(i) inhibition of apoptosis;(ii) promotion of proliferation.Anti-AKT Antibody is ideal for investigators involved in Cell Signaling,Cancer,Neuroscience,Signal Transduction research. |
| Uniprot ID | P31749/P31751/Q9Y243 |
| 推荐稀释比 | ELISA:User Optimized Flow Cytometry:User Optimized IHC:1:500 - 1:2,000 IF Microscopy:1:500 - 1:2,000 WB:1:1,000 - 1:5,000 |
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