产品货号：
Z10513
中文名称：
AFAP1抗体
英文名称：
Anti-AFAP1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AFAP1 Antibody |
| 指标别名 | AFAP;AFAP 110;AFAP1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | AFAP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AFAP1.The immunogen is located within amino acids 30 - 80 of AFAP1. |
| 计算分子量 | 81kDa |
| 成分 | AFAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | AFAP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src.AFAP1 has a fundamental role in actin cytoskeleton arrangement.It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains,including 2 pleckstrin homology (PH) domains,a Src homology 3-binding (SH3-binding) motif,and several SH2-binding motifs.It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells.AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis. |
| Uniprot ID | Q8N556 |
| 基因名全称 | Actin filament associated protein 1 |
| 蛋白名全称 | Actin filament associated protein 1 |
| 推荐稀释比 | AFAP1 antibody can be used for detection of AFAP1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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