产品货号：
Z10486
中文名称：
DyLight488标记ADO抗体
英文名称：
Anti-ADO DyLight 488 Conjugated Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ADO DyLight 488 Conjugated Antibody |
| 指标别名 | 2 aminoethanethiol dioxygenase;ADO;C10orf22;Cysteamine dioxygenase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | FCM |
| 基因名称 | ADO |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ADO recombinant protein (Position:E49-E261).Human ADO shares 90.1% amino acid (aa) sequence identity with mouse ADO. |
| 偶联物 | DyLight 488 |
| 激发/发射光谱 | Amax=488nm;Emax=515～545nm |
| 成分 | Each?vial?contains?50% glycerol,0.9%?NaCl,0.2%?Na2HPO4,0.02%?NaN3. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | At -20?C for one year from date of receipt.Avoid repeated freezing and thawing.Protect from light. |
| 背景资料 | Human thiol dioxygenases include cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO).CDO adds 2 oxygen atoms to free cysteine,whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine.It is demonstrated that mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine.Recombinant Ado was shown to bind iron.Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine.Similar results were found with human ADO.When endogenous expression of ADO was reduced by RNA-mediated interference,hypotaurine production decreased.It is also noted that the demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity. |
| Uniprot ID | Q96SZ5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Flow cytometry (FCM) 1～3μg/1×106 cells |
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