产品货号：
Z10409
中文名称：
ACVR1B抗体
英文名称：
Anti-ACVR1B Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ACVR1B Antibody |
| 指标别名 | activin A receptor;type IB;Activin receptor like kinase 4;Activin receptor type 1B;Activin receptor type IB;ACTR IB;ACTRIB;ACVR1B;ACVRLK4;ALK 4;ALK4;SKR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | ACVR1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ACVR1B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human ACVR1B.The immunogen is located within amino acids 140 - 190 of ACVR1B. |
| 计算分子量 | 57kDa |
| 成分 | ACVR1B Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ACVR1B Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors.ACVR1B,also known as activin receptor-like kinase 4 (ALK4),is a type I receptor for activin and plays major roles in cell differentiation,growth arrest and apoptosis.Like another type I activin receptor ACVR1C,ACVR1B can mediate signaling by ligands such as Nodal,Xnr1,GDF-1/3,activin B and activin AB.In Xenopus embryos,expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands,while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling,suggesting that the ACVR1B and ACVR1C possess distinct functions. |
| Uniprot ID | P36896 |
| 基因名全称 | Activin A receptor type IB |
| 蛋白名全称 | Activin A receptor type IB |
| 推荐稀释比 | ACVR1B antibody can be used for detection of ACVR1B by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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