产品货号:
Z10378
中文名称:
Acetylcholinesterase/ACHE抗体
英文名称:
Anti-Acetylcholinesterase/ACHE Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Acetylcholinesterase/ACHE Antibody |
指标别名 | Acetylcholinesterase;ACHE;ARACHE;N ACHE;YT |
克隆性 | Polyclonal |
检验物种 | human,mouse,rabbit,rat |
应用范围 | IHC |
基因名称 | ACHE |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ACHE (592-614aa SSYMVHWKNQFDHYSKQDRCSDL),different from the related mouse and rat sequences by one amino acid. |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ACHE is also known as Acetylcholinesterase.And Acetylcholinesterase hydrolyzes the neurotransmitter,acetylcholine at neuromuscular junctions and brain cholinergic synapses,and thus terminates signal transmission.It is also found on the red blood cell membranes,where it constitutes the Yt blood group antigen.Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties,but differ in their oligomeric assembly and mode of cell attachment to the cell surface.It is encoded by the single ACHE gene,and the structural diversity in the gene products arises from alternative mRNA splicing,and post-translational associations of catalytic and structural subunits.The major form of acetylcholinesterase found in brain,muscle and other tissues is the hydrophilic species,which forms disulfide-linked oligomers with collagenous,or lipid-containing structural subunits.The other,alternatively spliced form,expressed primarily in the erythroid tissues,differs at the C-terminal end,and contains a cleavable hydrophobic peptide with a GPI-anchor site.It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. |
Uniprot ID | P22303 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | acetylcholinesterase (Yt blood group) |
蛋白名全称 | Acetylcholinesterase |
推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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