产品货号：
Z10345
中文名称：
ACE2抗体
英文名称：
Anti-ACE2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ACE2 Antibody |
| 指标别名 | ACE related carboxypeptidase;ACE2;ACEH;Angiotensin converting enzyme 2;Metalloprotease MPROT15 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ACE2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-ACE2 antibody was raised against a peptide corresponding to 17 amino acids near the center of human ACE2.The immunogen is located within amino acids 180 - 230 of ACE2. |
| 计算分子量 | 92kDa |
| 成分 | ACE2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ACE2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular,renal,and myocardial physiology.In contrast to its homolog ACE,ACE2 expression is restricted to heart,kidney,and testis.Recently.ACE2 has also been shown to be a functional receptor of the SARS coronavirus.Homology modeling shows 2019-nCoV has a similar receptor-binding domain structure as SARS-CoV,which suggests COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans for infection. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7,unlike ACE,which converts AngI to AngII.While the role of these vasoactive peptides is not well understood,lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility,indicating its importance in regulating heart function. |
| Uniprot ID | Q9BYF1 |
| 基因名全称 | Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| 蛋白名全称 | Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| 推荐稀释比 | WB:1～2μg/mL;IHC:2μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in human samples;Immunofluorescence in human and rat samples.All other applications and species not yet tested. |
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