产品货号：
Z10287
中文名称：
AAK1抗体
英文名称：
Anti-AAK1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AAK1 Antibody |
| 指标别名 | KIAA1048;AP2-associated protein kinase 1;Adaptor-associated kinase 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat,monkey |
| 应用范围 | WB,IHC,IF,ELISA |
| 基因名称 | AAK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human AAK1 |
| 计算分子量 | 104KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | AP2-associated protein kinase 1 (Aak1) is a member of the Ark1/Prk1 subfamily of Ser/Thr protein kinases that are thought to regulate endocytosis by phosphorylating the accessory endocytic components.Aak1 interacts with and phosphorylates the mu2 subunit of the AP-2 complex,which promotes binding of the AP-2 to tyrosine based (Yxxphi) internalization motif-containing receptors and subsequent receptor endocytosis.At least two isoforms of Aak1 are known to exist;the longer isoform contains an extended carboxy-terminus that contains an additional clathrin-binding domain.Overexpression of this long isoform or Aak1 depletion by RNA interference impairs transferrin recycling from the early/sorting endosome,suggesting that Aak1 functions at multiple steps of the endosomal pathway by regulating transferrin internalization and its recycling back to the plasma membrane. |
| Uniprot ID | Q2M2I8 |
| 基因名全称 | AP2-associated protein kinase 1 |
| 蛋白名全称 | AP2-associated protein kinase 1 |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:100～1:300 IF 1:200～1:1000 ELISA 1:20000 |
相关搜索：AAK1抗体，AAK1多抗，Anti-AAK1 Antibody