产品货号:
Z10272
中文名称:
ADAM12抗体
英文名称:
Anti-ADAM12 antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ADAM12 antibody |
指标别名 | ADAM 12;ADAM12;MCMP;MCMPMltna;Meltrin alpha;MLTN;MLTNA |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC,ICC/IF,IP,Direct ELISA |
基因名称 | ADAM12 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human ADAM12 Polyclonal recombinant protein (Position:W34-H351). |
实际分子量 | 80KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ADAM12(Disintegrin and metalloproteinase domain-containing protein 12),also known as MLTN,is an enzyme that in humans is encoded by the ADAM12 gene.This gene encodes a member of the ADAM(a disintegrin and metalloprotease) protein family.Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins,and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions,including fertilization,muscle development,and neurogenesis.This gene has two alternatively spliced transcripts:a shorter secreted form and a longer membrane-bound form.The shorter form is found to stimulate myogenesis.By RT-PCR and immunoblot analyses that expression of mouse Adam12 increases during muscle regeneration,while the levels of other ADAMs remain constant.Immunofluorescence analysis revealed staining of small,newly formed muscle fibers in regenerating but not normal adult muscle cells.By using of fluorescence in situ hybridization,the ADAM12 gene is mapped to human chromosome 10q26.3. |
Uniprot ID | O43184 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 ImmunoPrecipitation (IP) 1:50 Direct ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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