产品货号:
Z10263
中文名称:
ADAM10抗体
英文名称:
Anti-ADAM10 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ADAM10 Antibody |
指标别名 | AD10;ADAM 10;ADAM10;CD156c;CDw156;HsT18717;kuz;Kuzbanian protein homolog;MADM |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | ADAM10 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-ADAM10 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human ADAM10.The immunogen is located within the last 50 amino acids of ADAM10. |
计算分子量 | 84kDa |
成分 | ADAM10 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ADAM10 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Proinflammatory cytokine tumor necrosis factor-alpha (TNF-汐) contributes to a variety of inflammatory responses and programmed cell death.Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders,including a T-cell lymphoma.TNF-汐,notch and its ligand delta are all membrane-bond molecules,which are cleaved by proteases to release mature proteins or functional receptor.ADAM10,a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease),was recently identified to cleave TNF-汐,notch and its ligand delta.The genes encoding human,mouse,and bovine ADAM10 were recently cloned and designated ADAM 10,kuzbanian (KUZ),and MADM,respectively.ADAM10 mRNA is expressed in a variety of human and bovine tissues. |
Uniprot ID | O14672 |
基因名全称 | ADAM metallopeptidase domain 10 |
蛋白名全称 | ADAM metallopeptidase domain 10 |
推荐稀释比 | WB:1μg/mL;IHC:2μg/mL;IF:10μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunofluorescence in human,mouse and rat samples.All other applications and species not yet tested. |
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