产品货号:
Z10235
中文名称:
AIFM3抗体
英文名称:
Anti-AIFM3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AIFM3 Antibody |
指标别名 | AIFL;AIFM3;Apoptosis inducing factor 3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | AIFM3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | AIFM3 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human AIFM3.The immunogen is located within the first 50 amino acids of AIFM3. |
计算分子量 | 67kDa |
成分 | AIFM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | AIFM3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis,also known as programmed cell death,plays major roles in development and normal tissue turnover in addition to tumor formation.Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3).AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria.Unlike AIF,AIFM3 does not translocate to the nucleus upon induction of apoptosis.However,overexpression of AIFM3,like AIF,induced cytochrome c release from the mitochondria,cleavage of caspase 3,and ultimately apoptosis,indicating AIFM3 induces apoptosis through caspase activation.Multiple isoforms of AIFM3 are known to exist. |
Uniprot ID | Q96NN9 |
基因名全称 | Apoptosis-inducing factor,mitochondrion-associated,3 |
蛋白名全称 | Apoptosis-inducing factor,mitochondrion-associated,3 |
推荐稀释比 | AIFM3 antibody can be used for the detection of AIFM3 by Western blot at 0.5 and 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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