产品货号：
Z10231
中文名称：
AIPL1抗体
英文名称：
Anti-AIPL1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AIPL1 Antibody |
| 指标别名 | AIPL1;AIPL2;LCA4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | AIPL1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Aipl1 antibody was raised against a 18 amino acid synthetic peptide near the center of the human Aipl1.The immunogen is located within amino acids 140 - 190 of Aipl1. |
| 计算分子量 | 44kDa |
| 成分 | Aipl1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Aipl1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Aipl1 was initially identified as a protein implicated in Leber congenital amaurosis (LCA),an autosomal recessive disorder thought to be caused by the abnormal development of photoreceptors.Aipl1 is a tetratricopeptide repeat protein that is highly homologous to ARA9,a protein involved in the HSP90-mediated nuclear translocation and transactivation of the aryl hydrocarbon receptor.Aipl1 has also been found to function as part of a chaperone heterocomplex,interacting with Hsp90 and Hsp70.Aipl1 also associates with the cell cycle regulator NUB1.It is thought that Aipl1 cooperates with Hsp70 but not Hsp90 to suppress the formation of NUB1 inclusions,and these interactions are necessary in the normal photoreceptor maturation,as mutations that lead to LCA also compromise the interactions with the Hsp chaperones.At least three isoforms of Aipl1 are known to exist. |
| Uniprot ID | Q9NZN9 |
| 基因名全称 | Aryl hydrocarbon receptor interacting protein-like 1 |
| 蛋白名全称 | Aryl hydrocarbon receptor interacting protein-like 1 |
| 推荐稀释比 | Aipl1 antibody can be used for detection of Aipl1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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