产品货号：
Z10179
中文名称：
ADAP/FYB1抗体
英文名称：
Anti-ADAP/FYB1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ADAP/FYB1 Antibody |
| 指标别名 | ADAP;Fyb;FYN binding protein;p120/p130;SLAP130 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | FYB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ADAP antibody was raised against a 20 amino acid synthetic peptide from near the carboxy terminus of human ADAP.The immunogen is located within amino acids 640 - 690 of ADAP. |
| 计算分子量 | 85kDa |
| 成分 | ADAP Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ADAP Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion.TCR stimulation promotes the formation of a multi-protein complex containing CARMA1,MALT1,and BCL-10,which through the association of ADAP,ultimately activates the NF-百B family of transcription factors.More recent experiments have shown that ADAP controls optimal T cell proliferation,cytokine production,and expression of the Bcl-2 family member Bcl-x(L),suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation.At least three isoforms of ADAP are known to exist. |
| Uniprot ID | O15117 |
| 基因名全称 | FYN binding protein (FYB-120/130) |
| 蛋白名全称 | FYN binding protein (FYB-120/130) |
| 推荐稀释比 | ADAP antibody can be used for detection of ADAP by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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